颅底脊索瘤的MRI诊断

MRI Diagnosis of Basicranial Chordoma

目的 研究颅底脊索瘤的MRI表现 ,探讨其MRI诊断价值。资料与方法 回顾性分析经手术病理证实的 17例颅底脊索瘤的MRI表现 ,13例行CT检查。结果 颅底脊索瘤发生在斜坡 11例 (6 4 .7% ) ,鞍区 6例(35 .3% ) ;肿瘤形态以类圆形分叶状为主 (88% ) ;病变呈不均匀长T1、长T2 信号 ,病灶内可见囊变、出血、钙化灶 ;病变侵犯邻近结构器官如 :斜坡、垂体、海绵窦等 ;MRI增强扫描示病变呈持续性“蜂房样”不均匀强化 10例 ,均匀强化2例。结论 MRI可清晰显示颅底部脊索瘤的部位、大小、范围、内部结构及与周围神经、血管的关系 ,具有较高的敏感性和一定特征性 。

Objective To discuss MRI manifestations of chordoma located at the base of skull, to evaluate MRI in the diagnosis of the disease.Materials and Methods MRI findings in 17 patients with pathologically-proved basicranial chordoma were retrospectively analyzed. Additional CT scanning was performed in 13 cases.Results The lesions were located at clival region (n=11, 64.7%) or sella turcica region (n=6, 35.3%). In 88% of cases, the tumor was oval and lobulated. The tumor showed inhomogeneous long T 1 and long T 2 signal, and cystic degeneration, hemorrhage and calcification could be seen within the lesion. The adjacent structures, such as clivus, pituitary and cavernous sinus, etc. were involved. On enhanced MRI, the lesions showed continuous inhomogeneous “honeycomb” enhancement (n=10) or homogeneous enhancement (n=2).Conclusion MRI can well display the location, size, extent, interior structure of the tumor, as well as its relationship with the adjacent nerves and vessels, which are very helpful in selecting proper surgical management and in assessing its prognosis.