血管内支架联合经皮腔内血管成形术在下肢闭塞性动脉硬化中的应用

Application of endovascular stent and percutaneous transluminal angio-plasty on arteriosclerosis obliterans of lower limb

目的在下肢闭塞性动脉硬化患者中血管内支架联合经皮腔内血管成形术的应用研究。方法选取2014年2月至2015年12月内蒙古民族大学附属医院下肢闭塞性动脉硬化患者72例,按照随机数字表法分为研究组(n=36)和对照组(n=36)。对照组患者应用常规保守治疗方案进行治疗,研究组在此基础上应用血管内支架联合经皮腔内血管成形术方案进行治疗。观察、比较2组患者治疗后临床效果,治疗前后跛行距离、踝肱指数情况和术后相关并发症的发生情况。结果治疗后,研究组患者的总有效率和对照组相比较,差异具有明显统计学意义(P<0.05)。研究组患者的跛行距离和踝肱指数比治疗前明显增加,并且改善水平比对照组更优,差异具有明显统计学意义(P<0.05)。研究组患者并发症的总发生率比对照组患者更少(P<0.05)。结论应用血管内支架联合经皮腔内血管成形术治疗下肢闭塞性动脉硬化患者,治疗效果较佳,可以改善下肢闭塞性动脉硬化患者的跛行距离和踝肱指数,并且支架的通畅率良好。

Objective To study on the application of endovascular stent and percutaneous transluminal angio-plasty in patients with arteriosclerosis obliterans of lower limbpatients. Methods From February 2014 to December 2015, 72 patients with arteriosclerosis obliterans of lower limb in our hospital were divided into study group(n=36) and control group(n=36) according to random number table method. Patients in the control group were treated with routine conservative treatment, and the study group was treated with endovascular stent and percutaneous transluminal angio-plasty on the basis of routine conservative treatment. The clinical effect after treatment, claudication distance and anklebrachial index before and after the treatment, and the postoperative complications were observed and compared between the two groups. Results After treatment, the total efficiency of the study group was compared with that of the control group, and difference was significant(P<0.05). Claudication distance and ankle-brachial index in study group were significantly higher than that before treatment, and the level of improvement was better than that in the control group, the difference was significant(P<0.05). The total incidence of complications in the study group was less than that in the control group(P<0.05). Conclusions The application of endovascular stent and percutaneous transluminal angio-plasty in patients with arteriosclerosis obliterans of lower limb have a better effect. It can improve the claudication distance and ankle-brachial index in the patients with arteriosclerosis obliterans of lower limb, and the stent patency rate is good.