血管内射频消融治疗血栓闭塞性脉管炎疗效观察

Efficacy of endovascular radiofrequency ablation for thromboangiitis obliterans

目的本研究旨在评估血管内射频消融(ERA)治疗血栓闭塞性脉管炎(TAO)的疗效。方法回顾性收集2013年1月至2018年10月行腔内血管开通后应用ERA治疗212例单侧TAO患者的临床资料,评估患者术后疼痛评分、踝肱指数(ABI)及复发率。结果术后疼痛评分明显下降(P<0.001)。术后即刻ABI、术后2周及术后3年ABI均显著高于术前ABI(P<0.001)。此外,术后2周和术后3年ABI值均明显高于术后即刻ABI(P<0.001)。术后3年随访期间复发32例(15.5%)。结论 ERA用于治疗TAO效果显著,无并发症发生,值得临床推广应用。

Objectives This study was designed to evaluate the efficacy of radiofrequency ablation(ERA)in the treatment of thromboangiitis obliterans(TAO).Methods The clinical data of 212 patients with unilateral TAO who underwent RFA treatment from January 2013 to October 2018 were retrospectively reviewed.The postoperative pain score,ankle index(ABI),and recurrence rate were evaluated.Results Postoperative pain scores were significantly lower(P<0.001).Immediately after surgery,ABI,2 weeks postoperatively,and 3 years postoperatively,ABI was significantly higher than preoperative ABI(P<0.001).In addition,ABI values at 2 weeks postoperatively and 3 years postoperatively were significantly higher than those immediately after surgery(P<0.001).32 patients(15.1%)relapsed during the 3-year follow-up period.Conclusion The efficacy of ERA in the treatment of TAO is significant,no complications occur,and it is worthy of clinical application.