常规超声联合超声造影评估颈动脉低回声斑块与脑梗死的关系

The relationship between carotid hypoechoic plaque and cerebral infarction by conventional ultrasound combined with contrast-enhanced ultrasonography

目的应用常规超声联合超声造影技术评估颈动脉低回声斑块与脑梗死的关系。方法选取65例临床诊断脑梗死患者及55例非脑梗死患者,均行颈动脉常规超声及超声造影检查,比较组间颈动脉斑块厚度和新生血管分级,并分析颈动脉低回声斑块与脑梗死的关系,比较以低回声斑块厚度≥2.5 mm、超声造影分级>Ⅱ级预测脑梗死的灵敏度和特异度。结果脑梗死组颈动脉斑块厚度多≥2.5 mm,超声造影分级多>Ⅱ级,与非脑梗死组颈动脉斑块对比,差异有统计学意义(P<0.05);以低回声斑块厚度≥2.5 mm、超声造影分级>Ⅱ级预测脑梗死的灵敏度和特异度分别为82.92%、77.27%。结论颈动脉常规超声联合颈动脉超声造影是预测脑梗死的有效参数。

Objective To evaluate the relationship between carotid hypoechoic plaque and cerebral infarction by conventional ultrasound combined with contrast-enhanced ultrasonography(CEUS).Methods 65 patients with clinically diagnosed cerebral infarction and 55 patients with non-cerebral infarction were selected,and examined by conventional carotid ultrasound and CEUS.The thickness of carotid plaque and grades of neovascularization were compared.The relationship between carotid hypoechoic plaque and cerebral infarction was analyzed.And the sensitivity and specificity to prediction of cerebral infarction by the thickness of carotid hypoechoic plaque(cutoff value≥2.5 mm)and neovascularization grade(cut off value>2)were compared.Results The thickness of carotid plaque in the cerebral infarction group was mostly greater than or equal to 2.5 mm,and the grade of CEUS was mostly higher than grade II.Compared with the carotid plaque in the non-cerebral infarction group,there was a significant difference(P value is less than 0.05).The sensitivity and specificity to prediction of cerebral infarction by the thickness of carotid hypoechoic plaque(cutoff value≥2.5 mm)and CEUS grade(cut off value>2)were respectively 82.92%and 77.27%.Conclusion Conventional carotid ultrasound combined with carotid CEUS grade is an effective parameter for predicting cerebral infarction.