期刊文献+

鼻咽癌相关分子标志物的研究进展 被引量:2

Research Progress of Molecular Markers in Nasopharyngeal Carcinoma
原文传递
导出
摘要 鼻咽癌是我国南方常见的恶性肿瘤,其发生涉及多个阶段过程。虽然近年来鼻咽癌的诊断和治疗水平有明显提高,但鼻咽癌的死亡率仍然很高。随着现代分子生物学的发展,许多新的分子标志物的出现给鼻咽癌的预防、诊断、治疗和预后等各个方面带来了新的希望。全文就近年来一些鼻咽癌各阶段相关分子标志物的研究进展做一综述。 Nasopharyngeal carcinoma(NPC) is a common malignant tumor in southern China. Although the diagnosis and treatment of nasopharyngeal carcinoma have been greatly improved in recent years,the mortality of nasopharyngeal carcinoma is still high. With the development of molecular biology,many new molecular markers have been discovered,bringing new hope to the prevention,diagnosis,treatment and prognosis of nasopharyngeal carcinoma. This article reviews the research progress on the molecular markers related to nasopharyngeal carcinoma.
作者 朱宏明 尹丽 何侠 ZHU Hong-ming;YIN Li;HE Xia(Jiangsu Cancer Hospital,Jiangsu Institute of Cancer Research,Nanjing Medical University Affiliated Cancer Hospital,Nanjing 210009,China)
出处 《肿瘤学杂志》 CAS 2019年第2期82-85,共4页 Journal of Chinese Oncology
基金 国家自然科学基金(81672989 81702685)
关键词 鼻咽肿瘤 分子标志物 进展 ,nasopharyngeal carcinoma molecular marker progress
  • 相关文献

参考文献2

二级参考文献48

  • 1Ohno S, Ohno Y, Suzuki N, et al. Multiple roles of cyclooxygenase-2 in endometrial cancer [J]. Anticancer Res, 2005, 25(6A): 3679-87.
  • 2Chen WC, Mcbride WH, Chen SM, et al. Prediction of poor survival by cyclooxygenase-2 in patients with T4 nasopharyngeal cancer treated by radiation therapy: clinical and in vitro studies [J]. Head Neck, 2005, 27(6): 503-12.
  • 3Farooq M, Haq I, Qureshi AS. Cardiovascular risks of COX inhibition: current perspectives EJ]. Expert Opin Pharmacother, 2008, 9(8): 1311-9.
  • 4Herschman HR. Primary response genes induced by growth factors and tumor promoters[J]. Annu Rev Biochem, 1991, 60:281-319.
  • 5Williams CS, Mann M, Dubois RN. The role of cyclooxygenases in inflammation, cancer, and development [J]. Oncogene, 1999, 18 (55): 7908-16.
  • 6Turini ME, Dubois RN. Cyclooxygenase-2: a therapeutic target[J].Annu Rev Med, 2002, 53: 35-57.
  • 7Tan KB, Putti TC. Cyclooxygenase 2 expression in nasopharyngeal carcinoma: immunohistochemical findingg and potential implications[J]. J Clin Pathol, 2005, 58(5): 535-8.
  • 8Petersen C, Petersen S, Milas L, et al. Enhancement of intrinsic tumor cell radiosensitivity induced by a selective cyclooxygenase-2 inhibitor[J]. Clin Cancer Res, 2000, 6(6): 2513-20.
  • 9Raju U, Nakata E, Yang P, et al. In vitro enhancement of tumor cell radiosensitivity by a selective inhibitor of cyclooxygenase-2 enzyme: mechanistic considerations [J]. Int J Radiat Oncol Biol Phys, 2002, 54(3): 886-94.
  • 10Amir M, Agarwal HK. Role of COX-2 selective inhibitors for prevention and treatment of cancer [J]. Pharmazie, 2005, 60(8): 563-70.

共引文献39

同被引文献20

引证文献2

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部