经皮超声造影在乳腺癌前哨淋巴结诊断中的研究进展

Advances Identification on Sentinel Lymph Node in Breast Cancer by Percutaneous Contrast-Enhanced Ultrasound

前哨淋巴结(sentinel lymph node,SLN)是原发肿瘤淋巴引流的第一站淋巴结,乳腺癌SLN转移与否直接影响着患者的治疗方案及预后。在乳腺癌患者中,转移性SLN的识别是一个重要的预后因素。因此,SLN定位与定性尤为重要。常用定位SLN的方法有核素法及染料法等,这些方法均只能定位而不能定性,而超声造影既能定位SLN,又可以判定SLN是否转移。全文就乳腺癌前哨淋巴结超声造影的相关研究进展进行综述。

Sentinel lymph node(SLN)is the first stage of lymphatic drainage in primary tumor.The metastasis of SLN in breast cancer directly affects the treatment and prognosis of patients.In breast cancer patients,the identification of metastatic SLN is an important prognostic factor,which provides valuable information for the decision of adjuvant therapy.Therefore,the positioning and characterization of SLN is particularly important.The commonly used methods for locating SLN are nuclide method and dye method.These methods can only be localized and cannot be qualitatively determined,but contrast-enhanced ultrasonography can locate SLN,and determine whether or not SLN is metastasized.This article reviews the research progress on identification of sentinel lymph node by percutaneous contrast-enhanced ultrasonography in breast cancer.