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miRNA在食管癌放射敏感性中作用机制的研究进展 被引量：3

Progress on miRNAs in Regulating Radiosensitivity of Esophageal Cancer
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摘要 食管癌是我国常见的恶性肿瘤之一,放疗是食管癌主要的治疗手段,其疗效具有个体化差异,大量研究发现miRNA与食管癌放疗敏感性密切相关。全文对miRNA调节食管癌放疗敏感性的作用及机制进行概述。 Esophageal cancer is one of the most common malignant tumors in China.Radiotherapy is the main treatment of esophageal cancer,and its therapeutic effect has individual differences.A large number of studies have found that miRNAs are closely related to the radiosensitivity of esophageal cancer.This article summarizes the roles and mechanisms of miRNAs in regulating the radiosensitivity of esophageal cancer.
作者 田晓康 钱露茜 杜鸣宇 卢志伟 朱宏明 费倩 张文君 王燕 彭凡禹 叶劲军 何侠 尹丽 TIAN Xiao-kang;QIAN Lu-xi;DU Ming-yu;LU Zhi-wei;ZHU Hong-ming;FEI Qian;ZHANG Wen-jun;WANG Yan;PENG Fan-yu;YE Jin-jun;HE Xia;YIN Li(Jiangsu Cancer Hospital,Jiangsu Institute of Cancer Research,The Affiliated Cancer Hospital of Nanjing Medical University,Nanjing 210009,China;Xuzhou Medical University,Xuzhou 221000,China;The Fourth Clinical Medical College of Nanjing Medical University,Nanjing 210009,China)
机构地区 江苏省肿瘤医院 徐州医科大学 南京医科大学第四临床医学院
出处 《肿瘤学杂志》 CAS 2019年第8期744-747,共4页 Journal of Chinese Oncology
基金 江苏省青年医学人才项目(QNRC2016659) 江苏省卫计委面上项目(H201614) 江苏省高层次人才“六个一工程”科研项目(LGY2016024)
关键词 MIRNA 食管肿瘤 放射敏感性 分子标志物 miRNA esophageal cancer radiosensitivity molecular markers
分类号 R735.1 [医药卫生—肿瘤]
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  • 9Dai Z J, Gao J, Kang HF, et al. Targeted inhibition of mammalian target of rapamycin (mTOR) enhances radio- sensitivity in pancreatic carcinoma cells[J]. Drug Des Devel Ther, 2013(7): 149-159.
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肿瘤学杂志
2019年 第8期

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