肌注胃复安对胶囊内镜检查的影响

Effect of metoclopramide on examination of capsule endoscopy

目的探讨肌注胃复安对胶囊内镜检查的影响。方法我院2013年12月至2014.年7月接受胶囊内镜检查的患者共106例,用药组为胶囊内镜在胃内停留时间超过45分钟的受检者肌注甲氧氯普胺10 mg(n=61),未使用胃肠动力药的患者为对照组(n=45),比较两组患者胶囊内镜小肠通过时间及完成全小肠检查的比例。结果两组患者性别、年龄比较差异无统计学意义(P<0.05)。用药组平均小肠通过时间为(313±86)分钟,对照组为(309±94)分钟,差异无统计学意义(P=0.961)。用药组胶囊内镜滞留率为9.83%,高于对照组13.3%,但差异无统计学意义(P=0.574)。结论肌注胃复安不会影响胶囊的小肠通过时间,不影响诊断医生对疾病的诊断,有望提高胶囊内镜的总体完成率。

Objective To investigate the effect of metoclopramide on the process of capsule endoscopy(CE)examination.Methods One hundred and six patients had CE examination in our hospital from December 2013 to July 2014.The patients with stay time of capsule endoscopy in the stomach more than 45 minutes received intramuscular injection of lOmg metoclopramide(drug group,n=61).The process and outcomes of CE were compared between the drug group and control group.Results There were no significant differences in age and gender between the two groups.The mean small intestine transmit time of CE was(313±86)min and(309±94)min respectively in the drug and control groups with no significant difference(P=0.961).The failure rate of complete small intestine examination was 9.83%in the drug group,lower than13.3%in the control group,but there was no significant difference(P=0.574).Conclusion Intramuscular injection of metoclopramide will not influence the small intestine transmit time of CE and process of CE examination.Moreover,it might increase the success rate of CE examination.