摘要
目的 为气动左室辅助装置对犬心肌损伤的作用研究提供良好稳定的实验模型。方法 对40条犬麻醉后,开胸连接左房-左室辅助装置-升主动脉。结扎左冠状动脉前降支或/和回旋支,造成急性左心衰模型进行辅助。结果实验早期,由于麻醉、温度、容量、低血压、心肌活检等技术问题犬死亡率高,后期经过总结经验教训试验过程顺利。结论使用犬结扎左冠状动脉前降支或/和回旋支,造成急性左心衰进行辅助的模型是可靠的。
OBJECTIVE To Providie a fine and stable experimental model for the research on how left ventricle assist device. METHODS After anesthesia, open the dog thorax connect assist device ot the left atrium and ascending aorta, left heart failure was caused by ligating the left anterior descending coronary artery and( or) left circumflex coronary arter-y. RESULTS left heart assist was established smoothly of a much process. CONCLUSION Circulatory assist is effec-ture in induced heart failure models.
出处
《中国体外循环杂志》
2003年第4期229-230,共2页
Chinese Journal of Extracorporeal Circulation
基金
煤炭部资助项目(97-382)
