胸腔镜微创手术与开放手术治疗肺癌的同期临床对照研究

Comparative study of complete video-assisted thoracoscopic pneumonectomy and open pneumonectomy in treatment of lung cancer

目的探讨胸腔镜肺癌根治术的安全性、有效性与可行性。方法回顾性分析2011年10月至2014年10月本院收治的胸腔镜手术微创组103例和随机抽取常规开放性肺癌根治术开胸组105例肺癌患者临床资料。比较2组患者的手术持续时间、术中出血量、清扫淋巴结总数、术后置管时间、住院天数、并发症发生率、住院费用、疼痛指标与术后7 d生活质量指标。结果腔镜组与开放组患者在手术持续时间、术中出血量、清扫淋巴结总数、并发症发生率与住院费用上差异无统计学意义(P>0.05),而在术后置管时间、住院天数与术后疼痛指标及术后7 d生活质量指标比较上差异有统计学意义(P<0.05)。结论胸腔镜肺癌手术安全、有效、可行,与传统手术相比优势明显。

Objective To explore the safety, efficacy and feasibility of complete video-assisted thoracoscopic pneumonectomy in the treatment of lung cancer. Methods The clinical data of 103 cases of complete video-assisted thoracoscopic pneumonectomy and 105 cases of open pneumonectomy in the treatment of lung cancer in the hospital from October2011 to October 2014 were retrospectively reviewed and analyzed, including the operative time, blood loss, total number of sweeping lymph glands, insertion time, hospitalization days, incidence of complications, hospitalization expenses, pain index,and 7-day life quality index after the operation. Results There were no significant differences between the two operations in the operative time, blood loss, total number of sweeping lymph glands, incidence of complications, and hospitalization ex-penses(P>0.05). However, there were significant differences between the two operations in the insertion time, hospital stay, pain index,and 7-day life quality index after the operation(P >0.05). Conclusion The complete video-assisted thoracoscopic pneumonectomy is safer, more effective and more feasible than the open pneumonectomy in the treatment of lung cancer.