大豆磷脂对小鼠血液成分的影响

EFFECTS OF SOYBEAN PHOSPHOLIPIDS ON BLOOD COMPONENTS IN MICE

目的 : 观察大豆磷脂对小鼠血液成分的影响。方法 : 雄性小鼠 40只 ,分为 4组 ,按 2 .5、5、1 0 g/ kg bw剂量的大豆磷脂和生理盐水连续灌胃 1 8d后 ,小鼠尾部取血 ,测定白细胞、红细胞、血小板和血红蛋白等指标。结果 :1 0 g/ kg bw剂量大豆磷脂能明显提高小鼠血液中淋巴细胞的数量及百分数 ,增加血红蛋白的含量及浓度 ,减少血小板数量 ,而对白细胞和红细胞数量没有明显的影响 ;5g/ kg bw剂量大豆磷脂可明显提高淋巴细胞的百分数 ,增加血红蛋白的含量及浓度 ,而对白细胞、红细胞和血小板的数量没有明显的影响 ;2 .5g/ kg bw剂量大豆磷脂除可明显增加平均红细胞血红蛋白的含量外 ,而对其它的血细胞成分指标没有明显的影响。结论 : 大豆磷脂具有增加淋巴细胞数量和升高血红蛋白的作用 。

Objective: To observe the effects of soybean phospholipids on blood components in mice. Methods: Forty male mice were divided into 4 groups. Experimental mice were fed with different doses of soybean phospholipids (2.5, 5 and 10 g/kg bw) and the control mice were fed with normal saline by tube feeding for 18 days. White blood cells, red blood cells, platelets and hemoglobin as well as other blood components were measured. Results: The soybean phospholipid at dose of 10 g/kg bw could significantly increase lymphocytes, lymphocyte percentage, hemoglobin, mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration, significantly decrease platelets, but did not obviously cause effects on white blood cells and red blood cells. The soybean phospholipid at dose of 5 g/kg bw could significantly increase lymphocyte percentage, hemoglobin, mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration, but did not obviously affect white blood cells, red blood cells and platelets. The soybean phospholipid at dose of 2.5 g/kg bw could significantly increase mean corpuscular hemoglobin concentration, but did not obviously affect other indices of blood components. Conclusion: The soybean phospholipid can enhance immune function and increase hemoglobin and is valuable for use as a hematonic food.