急性心肌梗死心率变异与预后及临床的关系

Relationship between heart rate variability and clinical features and prognosis of acute myocardial infarction

目的 为探索急性心肌梗死 (AMI)时心率变异性 (HRV)变化规律及对AMI预后的临床意义。方法 检测 10 3例AMI患者症状发生 2 4小时内及 3周时的HRV时域及频域指标 ,并与 90例正常人进行对比。结果 AMI患者HRV明显低于对照组 (P <0 0 5 ) ;合并糖尿病、高血压病等 ,年龄大、梗死面积大、Killip分级差 ,HRV较小。发生心脏事件者HRV明显低于不发生心脏事件者。 结论 提示AMI时自主神经系统功能失衡 ,诱发心脏电生理紊乱 ,影响预后。

Objective In order to study evolution and recovery of heart rate variability (HRV) after acute myocardial infarction(AMI),and its correlation with prognosis of AMI.Methods Time and frequency domain measures of HRV were analyzed from 103 patients with AMI,both at 24th hour and 3rd week after the onset of AMI,comparing with those of 90 normal controls.Results HRV in AMI patients was significantly lower than that in normal controls( P <0.05);HRV in patients with cardiac death was lower than that in the survivals;Moreover,HRV in AMI patients with other clinical variables was also lower than that in just only AMI patients;Conclusions It is revealed that function of auto nervous system after AMI affacts the prognosis of AMI.