甲状腺癌术后疼痛的治疗

Treatment of the postoperation pain in thyroid gland cancer

目的 :评价氯诺昔康与曲马朵治疗甲状腺癌术后疼痛的效果及安全性。方法 :随机将 6 0例甲状腺癌手术患者分为L组和T组 ,接受PCA治疗。L组使用氯诺昔康 32mg/ 4 8h ,T组使用曲马朵 6 0 0mg/ 4 8h。结果 :两组于使用PCA后 4h、12h、2 4h、36h、4 8h的VAS疼痛评分、PHS术后疼痛评分差异无显著性 (P >0 .0 5 )。镇静度评分 :12h以后T组高于L组 (P <0 .0 5 )。术后镇痛副作用的发生率L组低于T组 ,2组差异有显著性 (P <0 .0 5 )。总体评价L组优于T组。结论 :氯诺昔康与曲马朵治疗甲状腺癌术后疼痛的效果相似 ,副反应低 ,使用氯诺昔康的满意度优于曲马朵。

Objective: To evaluate the effect and security of lornoxicam and tramadol in treating the postoperative pain of thyroid gland cancer. Methods: 60 patients with thyroid gland cancer operation were randomly divided into group L and group T and accepted PCA. Group L were received lornoxicam 32mg/48h, group T were received tramadol 600 mg/48h. Result:In 4h, 12h, 24h, 36h, 48h , VAS and PHS had no significant changes after PCA treatment(P>0.05). Sedation degree grade: group T was higher than group L after 12h ( P<0.05). The group L was fewer than group T in side effects , there were significant difference. The general estimate of group L was superior to that of group T.Conclusion: Lornoxicam and tramadol have similar effect in treating postoperative pain in thyroid gland cancer ,while lornoxicam is superior to tramadol in the satisfaction degree.