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联合吸入呋塞米、利多卡因对急性发作期支气管哮喘患者肺通气功能的影响 被引量:2

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摘要 目的 探讨联合吸入呋塞米 利多卡因对急性发作期支气管哮喘 (哮喘 )患者肺通气功能的影响。方法 将轻、中度急性发作期哮喘患者 60例随机分为A、B、C三组 ,各组 2 0例。A组 (对照组 )吸入生理盐水 10ml ,B组联合吸入呋塞米 5 0mg( 5ml,10mg/ml)和利多卡因 10mg( 5ml ,2mg/ml) ,C组吸入 0 0 5 %沙丁胺醇溶液 10ml。观察三组患者吸药后15min肺通气功能的变化。结果 吸药后 15minB、C组用力肺活量 (FVC)、第一秒用力呼气容积 (FEV1)、最大呼气流量(PEF)、5 0 %肺活量时最大呼气流量 (V50 )、2 5 %肺活量时最大呼气流量 (V2 5)等与正常预计值的百分比FVC %、FEV1%、PEF %、V50 %、V2 5%均显著高于吸药前 ,且显著高于A组吸药后。结论 联合吸入呋塞米 利多卡因可减轻气道阻塞 ,改善发作期哮喘患者肺通气功能 ,与吸入沙丁胺醇效果相当。
出处 《四川医学》 CAS 2004年第1期95-96,共2页 Sichuan Medical Journal
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  • 1[1]Crimi Prosperini G,Ciamarra I,et al. Changes in neurokinin A(NKA)airway responsiveness with inhaled frusemide in asthma[J].Thorax,1997,52(9):775~779
  • 2[2]Rodwell LT,Anderson SD,Spring J,et al.Effect of inhaled frusemide and oral indomethacin on the airway response to hypertonic saline change in asthmatic subjects[J].Thorax,1997,52:59~66
  • 3[3]Hunt LW,Swedlund HA,Gleich GJ.Effect of nebulized lidocaine on seve glucocorticoid-dependent asthma[J].Mayo Clin Proc,1996,71:361~368
  • 4[4]DeccoML,Neeno TA,HuntLW,et al.Nebulizd lidocaine in the treatment of severe asthma in children:a pilot study[J].Ann Allergy Asthma Immumol,1999,82:29~32

同被引文献19

  • 1翟芳芝,李玉.肿瘤坏死因子-α基因多态性与支气管哮喘相关性研究[J].山东医药,2004,44(25):4-6. 被引量:13
  • 2郭宇玲,周世良.肿瘤坏死因子α启动子基因多态性与支气管哮喘及其严重程度的相关性研究[J].江西医学院学报,2004,44(5):28-30. 被引量:3
  • 3赵海军,丁亚春,刘娅,史杰萍,刘华锋,张婕,成焕吉,崔燕南,侯松萍.肿瘤坏死因子启动子基因多态性与哮喘的相关性[J].吉林大学学报(医学版),2005,31(3):449-451. 被引量:4
  • 4Bradding P, Roberts J A, Britten K M, et al. Interleukin-4,-5, and -6 and tmnornecrosis faetoralpha in normal and asthmatie aJrways:evldenee for the human mast cell as a source of these cytokines[ J]. Am J Respir Cell Mol Bio1,1994,10(5) :471 -480.
  • 5Li YF, Gaudermlan WJ, Avol E, et al. As sociations of tumor necrosis factor G-308A with childhood asthma and wheezing[ J ]. Am J Respir Crit Care Med ,2006,173 ( 9 ) :970 - 976.
  • 6Hong SJ,Kim HB,Kang MJ,et al. TNF-alpha( -308 G/A)and CD14 (-159T/C) polymorphisms in the bronchial responsiveness of Korean children with asthma [ J ]. J Allergy Clin lmmunol, 2007, 119 ( 2 ) : 398 - 404.
  • 7Zhang JY, Dou C,Song YT, et al. Polymorphisms of tumor necrosis factor-alphaare associated with increased susceptibility to gastric cancer:a meta-analysis [ J ]. J Hum Genet ,2008,53 ( 6 ) :479 - 489.
  • 8Egger M,Davey SG, Schneider M,et al. Bias in mleta-analysis detected by a simple,graphical test[J]. BMJ,1997,315(7109) :629 -634.
  • 9Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias[J]. Biometrics, 1994,50(4) : 1088 - 1101.
  • 10Wang TN, Chen WY, Wang TH, et al. Gene-gene synergistic effect on atopicasthma: tumour necrosis factor-alpha-308 and lymphotoxin-al-pha-NcoI in Talwan's children [ J ]. Clin Exp Allergy, 2004,34 ( 2 ) : 184 - 188.

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