^(131)I内放射治疗32例甲状腺功能自主性腺瘤疗效观察

The Clinical Value of ^(131)I Radiotherapy for Autonomously Functioning Thyroid Nodule

目的评价131I内放射治疗甲状腺功能自主性腺瘤(autonomously functioning thyroid nodule,AFTN)的临床价值。方法 32例AFTN患者均按单一标准剂量(555 MBq)服用131I溶液,治疗后3、6、12月进行随访并比较疗效。结果 32例患者摄碘功能升高9例(28.2%),减低5例(15.6%),正常18例(56.2%)。经131I内放射治疗后,甲状腺结节缩小、消失以治疗后3月最明显。甲状腺功能血清学指标趋于正常。经131I治疗后3、6、12月32例患者痊愈率分别为78.1%、90.6%和96.9%。结论131I放射治疗操作简单、并发症少、疗效好,值得临床推广。

Objective To evaluate the clinical value in131 I radiation therapy for thyroid functional autonomy adenoma( autonomously functioning thyroid nodule adenoma,AFTN). Methods 32 cases of AFTN patients were treated by single standard dose( 555 MBq) taking iodine [131I]solution. All cases were followed up and compared the efficacy after treatmented 3rd month,6th month and 12 th month. Results 32 cases of patients with iodine uptake increased in 9 cases( 28. 2%),decreased in 5 cases( 15. 6%),normal in 18 cases(56.2%). After radiation therapy,thyroid nodules reduced gradually. The changes were most obvious at the first three months after therapy. Thyroid functional serological index tended to be normal. The total effectiveness of AFTN were 78. 1%,90. 6% and 89. 16%,respectively at131 I therapyed 3td month,6th month and 12 th month. Conclusion131 I radiation therapy had the advantages of simple operation,less complications and good curative effect in treating autonomously functioning thyroid nodule and it was worthy clinical promotion.