摘要
采用基本评价和补充评价的生物学评价试验 ,比较全面地评价了生物衍生组织工程骨支架材料的生物相容性。结果显示 :该材料细胞评级为 1级 ,无致敏作用 ,热原试验合格 ,遗传毒性试验未见异常 ,骨植入试验未见异常 ,溶血率为 0 6 1 % ,慢性毒性试验未见异常。
Biological compatibility of a biological derivation bone tissue engineering scaffold was all sidedly evaluated by biological test of basic and additional evaluation. Results showed that the grades of cell culture with the material were grade Ⅰ. There was no sensitization effect; no irritant reactions were found in test of genotoxicity and test of chronic toxicity, there was no irritant reaction to the material implanted in bone and the hemolytic rate was 0 61%. The results demonstrated that the biological derivation bone tissue engineering scaffold is a satisfactory biomaterial.
出处
《北京生物医学工程》
2003年第4期281-284,共4页
Beijing Biomedical Engineering
