空间环境对秀丽线虫行为及生长发育研究进展

Review on behavior and development of Caenorhabditis elegans in space environment

与秀丽线虫有关的研究开始于20世纪60年代,秀丽线虫作为模式生物是第一个完成基因测序的多细胞生物,普遍应用于各种环境对生理和行为学研究中。空间环境以微重力、强辐射作为特点,对秀丽线虫的生理及行为产生很大影响。本文总结了微重力和辐射引起秀丽线虫运动能力、寿命、能量代谢等方面基因表达变化的研究成果。秀丽线虫与人类的序列相似性高达40%,空间环境对秀丽线虫行为及生长发育的研究为空间环境对人类健康影响研究提供数据支持,也为空间损伤修复研究提供理论基础。

The research related to C. elegans began from the 1960 s. It 's the first multicellular organisms with sequenced genome. As a model organism,C. elegans is widely used in physiological and behavioral researches about environmental changes. Microgravity and strong radiation are two characteristics of space environment which has a significant impact on the growth and development of C.elegans. We sum up the result of the research related to the growth and development of C.elegans and the results of the behavior,life-span and expression changes of several proteins in simulated microgravity and radiation environment. C. elegans can respond to environmental change very quickly,so it is common biological material used in the space environment study. According to the previous study,C.elegans had a sequence similarity of 40% with human,and the research on the behavior and the development of C.elegans provide data support for human's health and theoretical foundation for space damage repair.