中药治疗心力衰竭分子机制研究进展

Research Progress in Molecular Mechanism of TCM in Treating Heart Failure

心力衰竭发病率持续升高,以利尿剂、强心剂、扩血管剂及血管紧张素转换酶抑制剂等为主的西药治疗效果不理想、不良反应较多。近年来,中药治疗心力衰竭成果突出。本文从中药复方、单味药、中药提取物3个方面对近5年中药治疗心力衰竭分子机制研究进行梳理,为临床治疗提供参考。

The incidence of heart failure continues to increase,and the efficacy of diuretics,cardiotonic agents,vasodilators,and angiotensin-converting enzyme inhibitors are not satisfactory,with a lot of adverse reactions.In recent years,TCM has achieved outstanding results in the treatment of heart failure.This article combed the molecular mechanism of TCM in treating heart failure in the past five years from TCM compounds,single Chinese materia medica and TCM extracts,and provided references for clinical treatment.