慢性阻塞性肺疾病并发肺部真菌感染26例临床分析

Clinical analysis of 26 cases with chronic obstructive pulmonary disease accompanied by pulmonary fungus infection

目的 探讨慢性阻塞性肺疾病 (COPD)并发肺部真菌感染的危险因素、诊断和治疗。方法 回顾性分析COPD并发肺部真菌感染 2 6例的临床资料。结果 COPD并发肺部真菌感染的危险因素为 :长期使用广谱抗菌药物及糖皮质激素 ,老年病人和合并糖尿病、肺结核等慢性基础疾病病人多见。结论 合理使用抗菌药物及糖皮质激素、及时早期诊断和抗真菌治疗 ,是降低COPD并发肺部真菌感染的重要措施。

Objective To study the risk factors,diagnosis and therapy for chronic obstructive pulmonary disease(COPD) accompanied by pulmonary fungus infection.Methods A retrospective analysis was given to the clinical data of 26 cases with chronic obstructive pulmonary disease accompanied by pulmonary fungus infection.Results The risk factors for the pulmonary fungus infection were related to the treatments with broadspectrum antibacterial and cortical hormone.The aged patients and the patients with chronic basic diseases such as diabetes mellitus and pulmonary tuberculosis were susceptible to pulmonary fungus infection.Conclusion Reasonable use of antibacterial and cortical hormone as well as early diagnosis and treating fungus infection would be important measures for decreasing pulmonary fungus infection in patients with chronic obstructive pulmonary disease.