摘要
目的探讨小儿氨酚黄那敏颗粒联合磷酸奥司他韦颗粒治疗小儿季节性流感的疗效以及安全性。方法将2016年9~12月我院收治的88例季节性流感患儿随机分为对照组和观察组,每组44例。对照组患儿以体重为标准给予磷酸奥司他韦颗粒2次/d,连续应用5 d;根观察组患儿以体重为标准联合应用小儿氨酚黄那敏颗粒和磷酸奥司他韦颗粒(氨酚黄那敏3次/d,连续应用3 d,奥司他韦剂量和用法与对照组相同)。对比两组患儿的临床疗效及不良反应。结果临床疗效方面观察组较对照组明显提高(P<0.05);两组患儿治疗前后均未出现不良反应。结论磷酸奥司他韦联合小儿氨酚黄那敏治疗季节性流感效果显著,并能有效防止发生高热惊厥和肺炎,减少发生并发症。
Objective To investigatethe efficacy and safety of paditaxel in combination with oseltamivir phosphate in children with seasonal influenza. Methods 88 cases of seasonal influenza were randomly divided into control group and observation group,44 cases in each group from September to December in 2016. The mice in the control group were treated with oseltamivir phosphate 2 times/d for 5 days. The children of the observation group were treated with the weight of the mice as the standard. Aminophenanthrene 3 times/d,continuous application 3d,oseltamivir dose and usage and control group the same). Comparison of the two groups of children with dinical efficacy and adverse reactions. Results The dinical efficacy of the observation group was significantly higher than the control group( P<0. 05); the two groups of children before and after treatment were not adverse reactions. Conclusion oseltamivir phosphate combined with paditaxel in children is effective in the treatment of seasonal influenza,and can effectively prevent the occurrence of febrile seizures and pneumonia,reduce the occurrence of complications.