泌尿系统感染患者的人群分布以及耐药性分析

The analysis of bacterial examination and drug allergy for recurrent urinary tract infection

目的了解我院泌尿系统感染患者的人群和细菌分布以及其耐药性分析。方法对我院2015年1月1日至2016年12月31日两年间分离出的108株病原菌作回顾性分析。结果本次研究共分离病原菌108株,其中革兰氏阴性杆菌78株(占:72.2%),大肠埃希氏菌和肺炎克雷伯氏菌ESBL检出率为:30.55%和2.8%,与相关报道一致[1]。大肠埃希氏菌大于60岁的女性患者占比高达:70.7%。革兰氏阴性杆菌对:阿米卡星,亚胺培南,呋喃妥因,头孢替坦,派拉西林/他唑巴坦,厄它培南的耐药很低,革兰氏阳性球菌对:利奈唑烷,替加环素,万古霉素的耐药率相当低。结论泌尿系统感染以大肠埃希菌为主,并且更多发生在老年女性患者,其耐药菌株分离率达到了:36.1%,因此我们必须重视细菌及药敏检测,为临床合理使用抗生素提供依据,降低耐药菌株的产生,提高泌尿系统细菌感染的治愈率。

Objective To discuss the effect of bacterial examination and drug allergy for recurrent urinary tract infection. Methods Choosed 54 cases of recurrent urinary tract infection patients to take bacterial examination to detect drug allergy. Analyze the drugs pathogenic bacteria resistance. Results There were detecting 49 bacteria,among these,37 gram negative bacilli( 12 escherichia coli,10 enterobacter cloacae,8 pseudomonas aeruginosa,7 Klebsiella). And there were 12 Gram-positive cocci( 5 staphylococcus aureus,4 enterococcus,3 Streptococcus. The drug resistance rate of negative bacilli were lower with imipenem,smacrodantin,tobramycin,cefepime. Conclusion The main pathogenic bacterium of recurrent urinary tract infection was negative bacilli. We should take pathogens identification for drug resistance for work evidence.