摘要
目的分析糖尿病肾病微量白蛋白尿期的危险因素。方法回顾性分析2015年至2016年西南医科大学附属中医医院内分泌科糖尿病患者314例,收集患者相关临床资料:年龄、糖尿病病程,眼底病变,血压,ACR(尿微量白蛋白/肌酐比值)等资料。分析糖尿病肾病微量白蛋白尿期的相关影响因素。结果两组患者糖尿病病程、收缩压(SBP)、舒张压(DBP)、LDL-C和HDL-C间差异有统计学意义(P<0.05),FPG、年龄及TG间差异无统计学意义(P>0.05)。Logistic回归分析显示,SBP、LDL-C是糖尿病肾病微量白蛋白尿期的独立危险因素(P<0.05),HDL-C是糖尿病肾病微量白蛋白尿期的保护因素(P<0.05)。结论 SBP、LDL-C是糖尿病肾病微量白蛋白尿期的危险因素。HDL-C是糖尿病肾病微量白蛋白尿的保护性因素。
Objective To analyze the risk factors of microalbumin in the urinary phase of diabetic nephropathy. Methods The clinical data of 314 patients with endocrine department diabetes in the affiliated traditional Chinese medicine hospital of Southwest Medical University from 2015 to 2016 were retrospectively analyzed. The clinical data were collected: age,diabetes course,ocular fundus lesions,blood pressure,ACR( urine microalbumin/creatinine ratio) and so on. The related factors of microalbumin in the urinary phase of diabetic nephropathy were analyzed. Results There were significant differences in diabetes course,systolic pressure( SBP),diastolic pressure( DBP),LDL-C and HDL-C between the two groups( P05). Logitic regression analysis shows that SBP and LDL-C are independent risk factors for the microalbumin urine phase of diabetic nephropathy. Conclusion SBP and LDL-C are risk factors for microalbumin in diabetic nephropathy. HDL-C is a protective factor for microalbuminuria in diabetic nephropathy.
关键词
糖尿病肾病
微量白蛋白尿期
危险因素
diabetic nephropathy
microalbumin urine phase
risk factors
