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NT-proBNP与急性心肌梗死PCI术后心律失常相关性

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摘要 目的探讨氨基末端脑钠尿肽(NT-proBNP)与急性心肌梗死(AMI)患者经皮冠状动脉介入(PCI)治疗后是否出现心律失常相关性。方法选取2017年12月至2018年12月广东省第二人民医院收治的60例行PCI的AMI患者,根据心律失常发生情况分为心律失常组与心律正常组,各30例。观察并比较两组肌酐、尿酸、ALT、AST、T-CHO、LDL-C水平,及术后1d、术后1周、术后1个月及3个月NT-proBNP水平和超声心动图指标,并分析两者的相关性。结果两组肌酐、尿酸、ALT、AST、T-CHO及LDL-C水平比较,差异无统计学意义(P> 0.05)。术后1 d和术后1周,两组NT-pro BNP水平比较,差异无统计学意义(P> 0.05);术后1个月和3个月,两组NT-pro BNP水平比较,差异有统计学意义(P <0.01)。术后1 d、术后1周、术后1个月和3个月,两组超声心动图指标比较,差异均有统计学意义(P <0.05)。心律正常组与NT-pro BNP水平无明显相关性,而NT-pro BNP水平与AMI患者患者心律失常呈负相关(P <0.05)。结论急性心肌梗死患者PCI术后常规血生化指标无指导意义,而NT-pro BNP与心律失常具有负相关性,对早期诊断具有指导意义。
出处 《现代医学与健康研究电子杂志》 2019年第6期75-76,共2页 Modern Medicine and Health Research
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