PET/CT在非霍奇金淋巴瘤临床分期中的价值

PET/CT Image Values in Clinical Staging of the Patients with Non-Hodgkin's Lymphoma

目的:探讨PET/CT在非霍奇金淋巴瘤(NHL)临床分期中的价值。方法:收集2012年5月/2015年2月我院收治的NHL患者142例。观察患者PET/CT分期情况,并与临床分期结果进行比较。分析单纯结内侵犯NHL分期情况、结外侵犯伴或不伴淋巴结侵犯的NHL分期情况。结果:142例NHL患者临床分期结果为:Ⅰ期8例,Ⅱ期34例,Ⅲ期40例,Ⅳ期60例;PET/CT分期结果为:Ⅰ期6例,Ⅱ期36例,Ⅲ期44例,Ⅳ期56例。其中,二者符合的分期例数为136例,符合率为95.77%。比较PET和同机CT在单纯结内侵犯NHL分期方面,差异无统计学意义(P>0.05)。两种方法比较,在结外侵犯伴或不伴淋巴结侵犯的NHL分期方面,差异有统计学意义(P<0.05)。结论:PET/CT在NHL临床分期中,能够准确检出受侵犯的淋巴结,又能够灵敏检出受侵犯的结外病变,与临床分期符合率较高,可用于辅助指导临床治疗。

Objective:To explore the PET/CT image value in clinical staging for the patients with non-Hodgkin's lymphoma(NHL).Methods:A total of 142 cases of NHL in our hospital from May 2012 to February 2015 were enrolled in this study.The results of PET/CT staging and clinical staging were compared.The staging of simple intranodal NHL and extranodal NHL with or without lymphonode involvement was analyzed.Results:The clinical staging results of 142 NHL patients showed that 8 cases were observed in I stage,34 cases were observed in II stage,40 cases were observed in Ⅲ stage,60 cases were found in Ⅳ stage;the staging results of PET/CT showed that 6 cases were found in I stage,36 cases were found in II stage,44 cases were found in Ⅲ stage,56 cases were found in Ⅳstage.The coincidence rate of PET/CT staging with clinical staging was 95.77%(136/142).Comparison of PET and CT staging for simple intranodal NHL indicated no statistical difference(P > 0.05),while the PET and CT staging results of extranodal NHL with or without lymphonode involvement were statistically significant different(P <0.05).Conclusion:The PET/CT image can accurately detect the involved lymphnodes and can sensitively detect the involved extranodal lesions.PET/CT staging has high coincidence rate with clinical staging,thereby it can be used to guide the clinical treatment.