养心生脉颗粒辅助治疗老年冠心病并发慢性心力衰竭效果观察

Effect of yangxin shengmai granule in the adjuvant treatment of senile coronary heart disease complicated with chronic heart failure

目的观察养心生脉颗粒辅助治疗老年冠心病(CHD)并发慢性心力衰竭(CHF)的临床效果。方法将2017年1月至2018年6月郏县第二人民医院收治的92例老年CHD并发CHF患者纳入研究,采用随机数表法将其分为A组和B组,各46例。A组患者接受常规治疗,B组患者加服养心生脉颗粒。对比两组患者治疗前后LVEDD、LVESD、LVESV、LVEF等心功能指标,统计两组患者治疗总有效率和不良反应发生率。结果治疗后B组患者LVEDD、LVESD、LVESV水平低于A组,LVEF水平高于A组,组间差异有统计学意义(P <0. 05); B组治疗总有效率(93. 48%)高于A组(80. 43%),组间差异有统计学意义(P <0. 05);两组患者治疗期间均未出现明显不良反应。结论养心生脉颗粒辅助治疗老年CHD并发CHF临床效果较好,可有效改善患者心功能,且不会增加用药风险,具有较高的临床推广价值。

Objective To observe the clinical effect of yangxin shengmai granule on elderly patients with coronary heart disease( CHD) complicated with chronic heart failure( CHF). Methods Ninety-two elderly CHD patients with CHF admitted to the Second People’s Hospital of Jiaxian from January 2017 to June2018 were included in the study. They were divided into group A and group B by random number table method,46 cases in each group. Patients in group A received routine treatment,while patients in group B received yangxin shengmai granule. The cardiac function indexes such as LVEDD,LVESD,LVESV and LVEF were compared between two groups before and after treatment. The total effective rate and the incidence of adverse reactions of the two groups were counted. Results After treatment,the levels of LVEDD,LVESD and LVESV in group B were lower than those in group A,and the levels of LVEF in group B were higher than those in group A( P < 0. 05). The total effective rate in group B( 93. 48%) was higher than that in group A( 80. 43%).There were significant differences between two groups( P < 0. 05). There was no significant adverse reaction during treatment in both groups. Conclusion Yangxin shengmai granule has a good clinical effect in the adjuvant treatment of CHD complicated with CHF in the elderly,which can effectively improve the cardiac function of patients without increasing the risk of medication,and has a high clinical popularization value.