机械通气治疗小儿急性肺损伤

A Clinical Observation of Using Mechanical Ventilation for Pedo-acute Lung Injury

目的:探讨小儿急性肺损伤(ALI)的临床治疗。方法:对本院综合ICU 1998年4月至2002年4月发生的22例小儿ALI的临床治疗情况进行回顾性分析。结果:本组22例小儿ALI采用呼吸末正压机械通气(PEEP)联合大剂量甲基强的松龙冲击治疗,有效率为86.36％;3例死亡,死亡率为13.64％,死于多器官功能不全综合征(MODS)。结论:机械通气治疗小儿ALI应选择最佳PEEP,动态监测动脉血气指标和X线胸片,在综合治疗基础上加用大剂量甲基强的松龙冲击治疗能收到较好的疗效。

Objective:To explore the clinic treatment of pedo-acute lung injury (pedo-ALI). Method:To analyze the clinical treatment of 22 patients with pedo-ALI retrospectively. Results:The effective rate was 86.36% in all 22 cases after mechanical ventilation with positive end-expiratory pressure (PEEP) treatment and large dose methylprednisolone impact therapy. 3 cases died from multiple organ dysfunction syndrome (MODS). The mortality rate was 13.64%. Conclusion:Better results were produced after arterial blood gas index and chest X ray supervised dynamically and feasible PEEP value selected and treated with large dose methylprednisolone impact therapy.