用酶标免疫法检验尿中绒毛膜促性腺激素的临床意义

Clinical Significance of ELISA in Detecting Urine Chorion Gonadotrophic Hormone

1989年1月～1990年12月,用酶标免疫检验法,对298例(686次)妇科急症病人尿中绒毛膜促性腺激素(HCG)检验中,筛查出宫外孕47例,先兆流产71例,均得到及时处理。在2例用HCG/HMG诱发排卵的患者中,用该法监视尿HCG,最早出现HCG(+)反应者是排卵后的第11天和第15天。40例晚期妊娠尿HCG均为阳性(≥25mIU/ml)。45例分娩后与15例人工流产术后均在5～6天尿HCG(-)。结果提示酶标免疫检验是具有快速、简便、准确和特异性强的特点,有很高的临床价值。

Using enzyme immunoassay, 686 urinary HCG of 298 patients with acute gynaecological diseases were tested from January 1989 to December 1990. Among them 47 cases of extrauterine pregnancy and 71 cases of threatened abortion yielded positive results. In 2 cases of HCG/HMG induced ovulation, the earliest urinary HCG positive reaction was found on the 11th and 15th day after ovulation respectively.All the urinary HCG of 40 cases with late pregnancy were positive (≥25mIU/ml).In all 45 post-partum and 15 cases after artificial abortion, the urinary HCG tur ned to be negative in 5～6 days. The result showed that the test could be accomplished with a rapid, simple and accurate reaction, and has a greater diagnostic value.