下降型可调钠透析在血透中的应用观察

Effect of Decling Sodium Profile on Dialysis Hypotension in Hemodialysis

目的 :观察可调钠血液透析在透析低血压的作用。方法 :14例稳定的维持性血液透析患者进行观察。7例患者先进行标准钠透析 (透析液浓度 14 0mmol/L) 2周 ,然后进行可调钠透析 (钠浓度由 14 8mmol/L呈阶梯下降至 138mmol/L) 2周 ,7例先行可调钠透析 2周 ,标准钠透析 2周 ,观察透析前后血钠浓度和血容量变化 ,透析中心率和透析低血压的发生。结果 :可调钠透析能够明显减少透析低血压及相关症状的发生 (P <0 0 5 ) ,可调钠组血容量改变较标准钠明显减少 (P <0 0 5 ) ,且透前透后血钠浓度无明显改变 (P >0 0 5 )。结论 :可调钠透析能有效减少透析低血压的发生 。

Objective:To study the effect of sodium profile on dialysis hypotension.Methods:14 stable patients on maintenance hemodialysis were studied.7 patients of 14 studied received hemodialysis according to the order as standard hemodialysis(SHD,dialysate=140mmol/L),sodium profile hemodialysis(PHD,dialysatedecreased from 148mmol/L to 138mmol/L by stages)for 2 weeks respectively,and the other 7 patients accepted hemodialysis as PHD,SHD for 2 weeks respectively.Blood sodium concentraton and blood volume change were examined before and after dialysis.Heart rate and dialysis hyptension have been observed.Results:sodium profile hemodialysis could decrease the episodes of hypotension(P<0.05).The blood sodium concentration after hemodialysis was not significantly changed compared with before hemodialysis(P>0.05).The SHD group was great difference in blood volume decrease than PHD group(P<0.05).Conclusion:SHD can prevent the occurrence of dialysis hypotension effectively and do not increase body weight during dialysis.