老年人黄斑变性的荧光和吲哚青绿血管造影特征比较

Comparison of characteristics between indocyanine green and fundus fluorescence angiography in patients with age-related macular degeneration

目的 对渗出型老年黄斑变性 (ARMD)的荧光血管造影和吲哚青绿血管造影特征进行比较和临床评价。 方法 诊断为渗出型ARMD患者 2 5例 ,35只眼 ,年龄 6 0～ 81岁 ,视力 :指数 / 30cm～ 1 0。所有患者均进行彩色眼底照相、荧光血管造影和吲哚青绿血管造影 ,比较和分析图像特征。 结果 诊断为典型脉络膜新生血管的 2 0只眼 ,其中荧光血管造影 5只眼 (14 3% ) ,吲哚青绿血管造影 15只眼 (4 2 9% )。在荧光血管造影诊断为隐匿型脉络膜新生血管的 2 0只眼中 ,吲哚青绿血管造影诊断为典型脉络膜新生血管的为 7只眼。荧光血管造影诊断为浆液性色素上皮脱离(PED )不伴脉络膜新生血管的 3只眼中 ,吲哚青绿血管造影证实其诊断仅 1只眼 ,其中 2只眼为典型脉络膜新生血管。荧光血管造影诊断为浆液性PED伴脉络膜新生血管 1只眼 ,而吲哚青绿血管造影诊断为隐匿型脉络膜新生血管。 结论 与荧光血管造影比较 ,吲哚青绿血管造影提高了对ARMD的脉络膜新生血管检出率和准确性 ,为临床早期治疗ARMD提供了帮助。

Objective To compare the characteristics between indocyanine green angiography (ICGA) and fundus fluorescence angiography ( FFA ) in patients with age-related macular degeneration ( ARMD ). Methods Twenty-five cases ( 35 eyes ) were diagnosed as exudative ARMD by ocular examination. Their age ranged from 60 to 81 years. The visual acuities were 1.0 at FC/30 cm before eye. We analyzed and compared the characteristics of FFA and ICGA in these patients. Results 5 eyes ( 14.3% ) with classic choroidal neovascularization ( CNV ) were found by FFA examination. 15 eyes ( 42.9% ) with classic CNV were found by ICGA examination. Of 20 eyes with occult CNV considered by FFA, 7 eyes had classic CNV by ICGA. Of 3 eyes considered as serous retinal pigment epithelial detachment ( PED ) without classic CNV by FFA, 1 eye had serous PED with classic CNV and 2 eyes had classic CNV by ICGA.1 eye was diagnosed as serous PED with CNV by FFA, and as occult CNV by ICGA. Conclusions ICGA raise detectability and accuracy of CNV in ARMD compared with FFA. It is contributive to early treatment in ARMD.