新生儿血小板减少症92例病因分析

The etiologic analysis for neonatal thrombocytopenia

目的 :探讨新生儿血小板减少症的病因和预后。方法 :回顾性分析 92例新生儿血小板减少症患者的临床资料。结果 :在同期住院新生儿中 ,新生儿血小板减少症的发病率为 12 .5 8% ,其发病因素以感染为首位 ,占 5 2 .2 % ,窒息占 2 0 .6 % ,溶血占 13%。 73.91%病人不用特殊治疗 ,随着原发病的治愈血小板回升正常 ,仅 2 6 .0 9%需应用激素或丙种球蛋白等特殊治疗 ,本组病例治愈率 92 .39% ,死亡率 7.6 1% ,均死于原发病或肺出血。结论 :新生儿血小板减少症的常见发病因素是感染、窒息、溶血 ,其预后良好 ,关键在于原发病的防治。

Objectives:To study the etiology and prognosis of neonatal thrombocytopenia. Methods:92 cases of neonatal thrombocytopenia during 2000～2003 in our hospital were analyzed. Results:Neonatal thrombcytopenia had the incidence of 12.58%.Among the 92 cases ,52.5% had infection,20.6% had asphyxia,13% had hemolytic disease. Conclusions:Infection,asphyxia,hemolytic disease were the main causes of neonatal thrombocytopenia.