摘要
目的 :探讨染色体异常及变异与不良生育史的关系。方法 :对深圳地区 16 5 7例因不良生育史就诊者取外周血 ,常规培养 ,制片后G显带行染色体核型分析。结果 :发现染色体异常核型 5 4例 ,异常发生率为 3.2 6 % ,染色体多态变异核型 6 3例 ,变异发生率为 3.80 %。染色体异常率在不良生育史群体中高于一般群体 (0 .5 %～ 1% )。结论 :染色体异常是导致不良生育史的重要原因之一。
Objective: To research for the relation between an abnormal history of reproduction and chromosal abnormality or cromosome polymorphisms. Method: Chromosome G-banding was performed to determine the karyotype of 1657 patients with an abnormal reproductive history from ShenZhen area. Results: Among them, 54 cases (3.26%) showed chromosomal abnormalities, and 63 cases (3.80%) had cromosome polymorphisms. Their chromosome abnormality frequency is higher than normal population(0.5%~1%). Conclusion: Chromosome abnormality is one of important causes for abnormal reproduction. Chromosome polymorphism also involve in abnormal reproduction.
出处
《河北医学》
CAS
2003年第11期986-988,共3页
Hebei Medicine
关键词
不良生育史
染色体异常
核型分析
染色体多态性
深圳地区
Abnormal reproductive history
Chromosomal abnormality
Karyotype analysis
Chromosome polymorphism
