丹参注射液并化疗治疗晚期非小细胞肺癌35例——附单纯化疗对照组30例

Clinical observation on salvia miltiorrhizae composita combined with chemotherapy in treating non-small cell lung cancer:attached 30 cases of the control group simply with chemotherapy

将 6 5例患者随机分为两组 ,进行前瞻性对比治疗 ,治疗组 35例 ,用丹参注射液联合化疗 ,对照组 30例 ,单用化疗 ,两组所用化疗方案基本相同。结果 :治疗组和对照组近期总有效率按WHO标准分别为 4 8 5 7%和4 6 6 7% (P >0 0 5 ) ,但临床症状改善与缓解治疗组较对照组明显 (P <0 0 5 ) ,毒副反应治疗组较对照组明显少而轻。结论

Methods:From December 1999 to December 2002 65 patients with non-small cel lung cancer were divided randomly into two groups,the treatment group,which consisted of 35 case using Chinese herbs,for example,salvia miltiorrhizae composita(SMC) combined with chemotherapy and 30 case of control group were treated by chemotherapy only.The protocol of chemotherapy used in the two groups was similar.Results:The total effective rate (CR+PR) of short term according to the WHO standards was as follows:that of the treatment group and the control group was 48.57% and 46.67% respectively (P>0.05).But improvement and lysis of the clinical symptom in the treatment group was evidenter than that in the control group(P<0.05),the side effect in the treatment group was less and milder than that in the control group.Conclusion:The combined therapy of Chinese herbs,for example,SMC and chemotherapy in the clinical was worth exploring further.