常规放疗后期递量加速超分割治疗鼻咽癌疗效观察(附76例报告)

The observation of the curative effects of treating nasopharyngeal carcinoma by incrementally accelerative supra-sectioning in the later phase of the conventional radiotherapy (76 cases attached)

目的 探讨鼻咽癌常规放疗后期递量加速超分割的治疗效果。方法 鼻咽癌患者 76例随机分为常规放疗后期递量加速超分割组 39例 ,常规放疗组 37例 ,超放组在常规放疗后 4周 ,实施递量超分割 3周 ,每分次量分别为 1.3、1.4、1.5Gy ,2次 /天 ,间隔≥ 6小时 ,5天 /周 ;常规组 2Gy/次 ,1次 /天 ,5天 /周。结果 两组 1、3年生存率差异有显著意义 ,1、3年局部控制率差异有显著意义和极显著意义。结论 鼻咽癌后期递量加速超分割可能是控制局部复发 ,提高生存率的有效方法。

Objective The purpose of this paper is to discuss the curative effects of treating nasopharyngeal carcinoma in the later phase of conventional radiotherapy.Methods 76 patients of nasopharyngeal carcinoma were randomly divided into two groups: 39 in the supra-sectioning group and 37 in the conventional radiotherapy group.The supra-sectioning group was treated with incrementally accelerative supra-sectioning for 3 weeks after a four week conventional radiotherapy.The dosages were respectively 1.3 , 1.4 and 1.5Gy .The patients were treated twice a day, with the interval no less than 6 hours.They were treated 5 days a week.The conventional radiotherapy group was treated with 2 Gy each time,once a day,5 days a week.Results The difference of the 1?3-year survival rates of the two groups was of significance and that of the 1?3-year local control rates was of significance and remarkable significance.Conclusion Therefore we've arrived at the conclusion that the incrementally accelerative supra-sectioning in the later phase of the treatment of nasopharyngeal carcinoma may well be an effective way of curbing local relapse of the cancer as well as improving the survival rate.