心理干预对青光眼患者焦虑、皮质醇及血液流变学的影响

Effects of Mental Intervention for Anxiety and Changes of Cortisol Level and Hemorrheology in Patients with Glaucoma

目的 :观察心理干预对青光眼患者焦虑情绪、血液流变学和皮质醇及术后前房恢复的影响。方法 :将入选住院 60例青光眼病人随机分为治疗组和对照组 ,给予 2组病人常规降低眼压下的青光眼手术治疗 ,治疗组同时实施支持性心理干预和放松训练等 ,观察治疗前后 2组病人的焦虑情绪、血液流变学和血皮质醇变化及术后前房恢复情况。结果 :治疗组患者焦虑情绪 (3 8 6± 7 2 42 1± 7 2 ,t =2 4,P <0 0 5 )、血液流变学 (t=9 2～ 3 0 ,P <0 0 1)和血皮质醇 (t=3 9,P <0 0 1)及前房恢复 (χ2 =5 9,P <0 0 1)较对照组有明显改善 ,且差异有差异性。结论 :心理干预可降低应激引起的青光眼患者的焦虑情绪和血皮质醇的分泌增加及血液流变学的改变 ,促进青光眼的好转。

Objective:To study the role of mental intervention on anxiety and changes of cortisol level and hemorrheology of patients with glaucoma.Methods:60 inpatients with glaucoma were divided into intervention group and control group.Both groups received routine therapy for glaucoma and operation. The intervention group also received psychological support and relaxation training before operation. Anxiety of both groups was measured by SAS, as well as cortisol level and indexes of hemorrheology before and after the operation.Results:Before intervention, the two groups were comparable in both mental state and cortisol level, as well as the indexes of hemorrheology. After operation, the intervention group had lower anxiety and cortisol level than the control,as well as the indexes of hemorrheology. The recovery time of anterior chamber after the operation was shorter in intervention group than in control group.Conclusions:Mental intervention is helpful for patients receiving operation for glaucoma in both anxiety decrease and recovery from the operation.