中西医结合治疗糖尿病足的临床观察

Clinical Observation on Treatment of Diabetic Foot by Integrative Chinese and Western Medicine

目的 :观察中西医结合治疗糖尿病足的临床疗效。方法 :将 6 3例糖尿病足患者随机分为治疗组33例和对照组 30例。两组患者均给予相同的基础治疗、扩张血管及抗凝治疗、外治法治疗 ,治疗组在此基础上加用中医辨证施治。结果 :治疗组显效 12例 ,有效 18例 ,无效 3例 ,总有效率 90 9% ;对照组显效 9例 ,有效 14例 ,无效 7例 ,总有效率 76 7% ;两组比较 ,差异有显著性 (χ2 =15 8,P <0 0 5 )。治疗组治疗后Ⅱ、Ⅲ、Ⅳ级例数减少 ,恢复为 0级例数增多 ,与对照组比较 ,差异有显著性 (P <0 0 5 )。治疗组溃疡大小、新鲜创面肉芽例数与对照组比较 ,差异有显著性 (P <0 0 5 )。两组治疗后空腹血糖 ,餐后 2h血糖均有改善 ,与治疗前比较 ,差异有显著性 (P <0 0 5 )。结论 :中西医结合治疗糖尿病足的疗效比单用西药治疗为好。

Objective: To observe the efficacy of integrative Chinese and western medicine (ICWM) in treating diabetic foot. Methods: Sixty-three patients were randomly divided into the treated group (n=33) and the control group (n=30). Both groups were treated by same baseline treatment with vasodilator, anti-agglutination agents and external treatment, to the treated group, Chinese drugs were given additionally according to the Syndrome Differentiation. Results: In the treated group, the treatment showed markedly effective in 12 patients, effective in 18 and ineffective in 3, the total effective rate being 90.0%, while in the control group, the corresponding numbers were 9, 14, 7 and 76.7%, comparison between the two groups showed significant difference (χ 2=15.8,P<0.05). The case number of Grade Ⅱ, Ⅲ and Ⅳ in the treated group reduced, and those recovered to Grade 0 increased, as compared with those in the control group, the difference was significant (P<0.05). Patients with healing of ulcerative wound and fresh wound granulation in the treated group, as compared with those in the control group, the difference was significant (P<0.05). Levels of fasting blood glucose and blood glucose 2 hrs after meal were all improved in both groups, which showed significant difference as compared with those before treatment (P<0.05). Conclusion: The efficacy of ICWM treatment in treating diabetic foot was better than the treatment of western medicine alone.