摘要
目的 :探讨牙龈卟啉单胞菌 Fim A基因型在牙周患者的分布情况。方法 :采用 PCR技术对 40例牙周患者龈下菌斑中牙龈卟啉单胞菌及其基因型进行检测。结果 :牙龈卟啉单胞菌在牙周患者的牙周袋内检出率为 87.5% ,牙龈卟啉单胞菌 Fim A各基因型在牙龈卟啉单胞菌携带者的检出率分别为 : 型2 2 .9% , 型 60 .0 % , 型 17.1% , 3 7.1% , 型未检出 ;基因 型在牙周袋内未单独检出 ,与基因 型混合感染。结论 :牙龈卟啉单胞菌 Fim A基因 型和 型是牙龈卟啉单胞菌在牙周病损部位的主要定植菌 。
Objective:To investigate the prevalenc e of Porphyromonas gingivalis and its FimA genotypes in Chinese periodontal pockets.Methods: Porphyromonas gingivalis and its FimA genotypes in periodontal pockets from 40 subjects with adult periodontitis were detected w ith PCR.Results: The prevalence of P gingivalis in periodontal poc kets was 87 5%. In the P gingivalis-positive subjects,the most prevalent FimA genotypes was genotype Ⅱ(60%),followed with genotype Ⅳ(37 1%), genotype Ⅰ(22 9%),genotype Ⅲ(17 1%),genotype Ⅴundetected.Genotype Ⅰ was always co -infected with genotype Ⅱ in the periodontal pockets.Conclusion:FimA genotype Ⅱ of P gingivalis was involved in the development of anult periodontitis.
出处
《中国微生态学杂志》
CAS
CSCD
2003年第6期338-339,共2页
Chinese Journal of Microecology
基金
国家自然科学基金资助项目 (编号 30 1 71 1 75)
