山羊脊神经后根逆向吻合生长的超微结构

The Ultrastructure of New Growing Nerve Fiber of the Spinal Nerve Dorsal Root of Goat after being Severed and Converse Anastomosis

目的 :探索山羊脊神经后根逆向吻合生长后的超微结构。方法 :选择山羊右侧L3 ～S1脊神经后根 ,每根取 1/ 2切断 ,然后将L3 与L5、L4与S1切断的脊神经后根的远端 ,用显微外科技术行端端吻合 ,4个月后取吻合段脊神经后根透射电镜观察。结果 :吻合区既有有髓鞘神经纤维通过 ,也有无髓鞘神经纤维生长。结论 :在蛛网膜下腔脊神经后根离断并逆向吻合后能和周围神经一样生长。山羊脊神经后根逆向吻合生长后 ,脊神经后根的微细结构发生变化 ,即在该脊神经后根纤维中 ,在外周段出现电兴奋传导方向相反的神经纤维 ,在中枢段出现来自拮抗肌的神经纤维 ,因此该脊神经后根的功能可能发生某些变化。

Objective: To explore the new growing nerve fiber's ultrastructure of the spinal nerve dorsal root after being severed and converse anastomosis. Method: Have the right side L_3～S_1 spinal nerve dorsal root be severed 1/2,the proximal cut end of severed spinal nerve dorsal root were inosculated , L_3 with L_5, L_4 with S_1, the new growing nerve fiber were observed by electron microscope. Result:There were both myelinated fiber and non myelinated fiber of nerve growing.Conclusion: Spinal nerve dorsal root can grow as well as peripheral nerve after being severed and converse anastomosis inosculated in subarachnoid space. Because there are the contrary direction electrical pulser and antagonist nerve fiber in the spinal nerve dorsal root after being severed and converse anastomosis, the function of the spinal nerve dorsal root will change.