摘要
微囊化包被组织细胞移植可发挥免疫隔离作用 ,为解决治疗疾病中的免疫排斥反应和移植物来源短缺提供了新途径。海藻酸钠 /多聚赖氨酸 /海藻酸钠 (APA)微囊是目前最成熟的微囊化技术 ,其高度的生物相容性和良好的免疫隔离作用 ,使得异种组织细胞或基因工程细胞移植成为可能 ,在神经内分泌及代谢疾病方面的研究取得了可喜的进展 ,具有广阔的应用前景。
The encapsulation of tissue or cells, which can develop an effective immunoisolation system, makes it possible to overcome the danger of immune rejection and the problems of donor shortage in transplantation of xeno- or allografts. Alginate-polylysine-alginate(APA) membranes have shown good qualities on protection, biocompatibility and semipermeability, so transplantation of xeno- or allografts and genetically engineered cells encapsulated in APA membranes may be possible for the treatment of some diseases,and the remarkable progress was made in the research of neuroendocrine and metabolism diseases.
出处
《解剖科学进展》
CAS
2003年第4期343-346,共4页
Progress of Anatomical Sciences
基金
国家自然科学基金 (No 30 0 60 0 34)
江西省自然科学基金 (No 0 1 4 0 1 2 6)
