国产甲孕酮改善肿瘤患者生存质量的临床报告

CONCOMITANT USE OF HOMEMADNE MEDROXYPROGESTRONE TO IMPROVING THE LIFE QUALITY OF CANAER PATIENTS

为改善肿瘤患者的生存质量,对31例实体瘤患者在行化疗、放疗同时并用国产醋酸甲孕酮(乐泰胶囊),320mg/d或480mg/d,共服用15～40d。结果食欲增加28例(90.32％),食量增加23例(74.19％),无食欲、食量减少病例。体重增加19例(61.13％)。上述不同的每日用药剂量和服药天数对体重变化的影响无统计学差异(P>0.05)。服药期间,未出现不能耐受的不良反应。由此表明乐泰胶囊改善肿瘤患者生存质量的作用与国外同类产品相似。

For improving life quality,concomitant use of medroxyprogestrone acetate (MPA) was adapted in a daily dose of 320mg or 480mg for a period of 15~40 days in 31 cancer patients receiving chemotherapy or radiotherapy. The rates of food intake increasing and weight gained were 74. 19% and 61. 13% respectively. No significant statistical difference in weight gained has been found between different daily doses of MPA and between different days of intaking MPA. The side effects were well tolerated.