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阻塞性睡眠呼吸暂停综合征正压通气治疗前后肾功能和电解质的变化 被引量:2

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摘要 目的 :观察阻塞性睡眠呼吸暂停综合征 (OSAS)正压通气治疗前后肾功能和电解质的变化情况。方法 :通过测定血 K+ 、Na+ 、Cl- ;尿 K+ 、Na+ 、Cl- 、自由肌酐清除率 (Ccr)、β2 -微球蛋白 (β2 - m G)、夜间尿量等分别观察 OSAS患者肾小球滤过功能及近、远端肾小管钠水重吸收功能。结果 :OSAS治疗组 2 0例治疗前夜尿量、夜尿 K+ 、Na+ 、Cl- 均高于正常 ,与最低血氧饱和度 (L sa O2 )、最长呼吸暂停时间 (L AT)的严重性呈正比关系。治疗组经一整夜正压通气(n CPAP)治疗后夜尿量及尿液中 K+、Na+、Cl-恢复正常。结论 :严重的 OSAS确实累及肾脏 。
出处 《包头医学院学报》 CAS 2003年第3期199-200,共2页 Journal of Baotou Medical College
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