CO中毒后迟发性脑病的临床与脑电图、脑CT分析

STUDY ON CLINICAL CHARACTERISTIC, EEC AND CT FEATURES OF PATIENTS WITH DELAYED ENCEPHALOPATHY AFTER ACUTE CARBON MONOXIDE POISONING

目的:探讨CO中毒后迟发性脑病的EEG和脑CT特征及对本病的诊断价值。方法:对63例CO中毒后迟发性脑病的临床与脑电图、脑CT特征进行分析。结果:CO中毒后迟发性脑病的临床主要表现为以痴呆为主的精神障碍,EEG表现为以额叶为主的广泛弥漫性高幅慢波及生理波减弱,阳性率为100％。脑CT主要以皮质下广泛的低密度改变及基底节区局灶性低密度影为特征,部分患者CT可正常。结论:EEG和CT能发现CO中毒引起的脑部形态及功能的变化,EEG对DEACMP的敏感性高于CT,EEG在早期诊断DEACMP上优于CT,可作为临床痊愈、判断预后的指标之一。

Objective: To explore the diagnostic value of EEC and CT in delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) . Methods: The clinical characteristic, EEC and CT data of 60 patients with DEACMP were analysed. Results: The main clinical manifestations of the disease were intellectual disturbances and personality disorders. EEC showed diffusing high amplitude slow wave, especially in fortal areas. CT showed that diffusing low density shadow in bilateral cerebral white matter, prominenly in globus pal-lidus or basal ganglia areas. Conclusions: EEC and CT were a safe judging method about structural - and -functional changes in the brain of DEACMP. EEC was demonstrated to be a powerful tool to diagnosis of deamp and showed a higher prognostic value than CT.