期刊文献+

预防接种与自身免疫病的关系

Vaccination and Autoimmune Diseases
原文传递
导出
摘要 感染与自身免疫性疾病之间的联系已引出一场争论 :疫苗是否也能激发自身免疫性疾病。有关这种风险有众多正反两方面的主张。在此复习感染诱导自身免疫病的相关机制 ,并对预防接种和自身免疫病之间的相对危险度进行评估。 The association between infection and autoimmune diseases has stimulated a debate as to whether such diseases might also be triggered by vaccines.There are numerous claims and counter claims relating to such a risk.Here we reviewed the mechanisms involved in the induction of autoimmunity and assessed the relative risk between vaccination and autoimmune diseases in human beings.
出处 《中国计划免疫》 2003年第6期370-374,共5页 Chinese Journal of Vaccines and Immunization
关键词 预防接种 自身免疫病 感染 疫苗 相对危险度 评估 Infection Vaccine Vaccination Autoimmune disease
  • 相关文献

参考文献27

  • 1[1]Jacobson D L,Gange S J,Rose N R,et al.Epidemiology and estimated population burden of selected autoimmune diseases in the United States[J].Clin Immunol Immunopathol,1997,84:223-243.
  • 2[2]Bach J F.The effect of infections on susceptibility to autoimmune and allergic diseases[J].N Engl J Med,2002,347:911-920.
  • 3[3]Nemazee D.Receptor selection in B and T lymphocytes[J].Annu Rev Immunol,2000,18:19-51.
  • 4[4]Panoutsakopoulou V,Sanchirico M E,Huster K M,et al.Analysis of the relationship between viral infection and autoimmune disease[J].Immunity,2001,15:137-147.
  • 5[5]Hemmer B,Jacobsen M,Sommer N.Degeneracy in T-cell antigen recognition:implications for the pathogenesis of autoimmune diseases[J].J Neuroimmunol,2000,107:148-153.
  • 6[6]Mason D.A very high level of crossreactivity is an essential feature of the T-cell receptor[J].Immunol Today,1998,19:395-404.
  • 7[7]Medzhitov R,Janeway C A Jr.Decoding the patterns of self and nonself by the innate immune system[J].Science,2002,296:298-300.
  • 8[8]Kissler S,Anderton S M,Wraith D C.Cross-reactivity and T-cell receptor antagonism of myelin basic protein-reactive T cells is modulated by the activation state of the antigen presenting cell[J].J Autoimmun,2002,19:183-193.
  • 9[9]Mizrahi T,Hauben E,Schwartz M.The tissue-specific self-pathogen is the protective self-antigen:the case of uveitis[J].J Immunol,2000,169:5971-5977.
  • 10[10]Theofilopoulos A N,Dummer W,Kono D W.T cell homeostasis and systemic autoimmunity[J].J Clin Invest,2001,108:335-340.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部