“益气活血通络方”治疗冠心病心绞痛41例临床观察

Clinical Observation on Treatment of 41 Cases of Coronary Heart Disease with Angina Pectoris with Yiqihuoxuetongluo Decoction

目的 观察“益气活血通络方”治疗冠心病心绞痛的治疗效果。方法 将 81例冠心病心绞痛患者随机分为治疗组 (4 1例 )和对照组 (4 0例 ) ,两者在年龄、性别分布、病程长短、心绞痛类型、心功能分级、伴随病变等方面具有可比性 (P >0 0 5 )。治疗组给予“益气活血通络方” ,水煎服 ,每次 15 0mL ,1日 2次 ;对照组给予消心痛 ,口服 ,每次 10mg ,1日 3次。结果 经 4周治疗 ,“益气活血通络方”治疗冠心病心绞痛症状总有效率为 85 37% ,显著高于对照组 6 2 5 0 % (P <0 0 5 ) ;两者均能降低硝酸甘油日耗量 ,但硝酸甘油减用率组间比较无显著性差异 (P >0 0 5 ) ;心电图疗效治疗组总有效率 4 6 34% ,对照组 4 2 5 0 % ,无显著性差异 (P >0 0 5 )。结论 “益气活血通络方”

Objective Clinical observation on the curative effects of Yiqihuoxuetongluo Decoction (aimed to enrich vital energy, activate blood circulation, clear main channels to promote vital energy circulation) for the treatment of coronary heart disease with angina pectoris was given. Methods Eighty one cases were randomly divided into the treatment group (including 41 cases) and the control group (including 40 cases). The two groups were well matched ( P >0.05) for age, sex, course of disease, angina types, cardiac functional grade and complications. The treatment group was given 150 ml Yiqihuoxuetongluo Decoction orally every time twice a day. The control group was given 10 mg Isosorbide Dinitrate every time, three times daily. Result After 4 weeks' treatment the total effective rate was 85 37% in the treatment group which was evidently higher than that of the control group (62 50%, P <0 05). Yiqihuoxuetongluo Decoction could reduce the consumption of nitroglycerin, but there was no obvious difference in dosage decreasing rate between two groups ( P >0 05). By the electrocardiogram (ECG) the total effective rate was 46 34% in the treatment group and 42 50% in the control group. There was no clear difference ( P >0 05). Conclusion Yiqihuoxuetongluo Decoction could improve availably the symptoms of coronary heart disease with angina pectoris.