GP87在胃癌及胃癌前病变患者胃液和粪便中的表达

Study on Expression of GP87 in the Gastric Fluid and Feces of Patients with Gastric Cancer and Gastric Precancerous Conditions

目的 :探讨 GP87在胃癌及胃癌前病变患者胃液和粪便中表达的诊断价值。方法 :采用酶联免疫吸附测定 ( ELISA)法检测胃癌及胃癌前病变患者胃液、粪便中的 GP87水平。结果 :阳性率最高者为胃癌组 ,其次为不典型增生组 ,肠化生组及萎缩性胃炎组 ,浅表性胃炎组及正常对照组则明显低于以上各组。结论 :检测

Objective:In order to explore the expression of GP87 in the gastric fluid and feces of patients with gastric cancer and gastric precancerous conditions and to determine the diagnostic value in the above patients. Methods:The levels of GP87 in the gastric fluid and feces of patients with gastric cancer and gastric precancerous conditions were detected by ELISA. Results:The positive rate was the highest ingastric cancer group and secondly in gastric precancerous condition group. The positive rates of superficial gastritis group and control group were significant lower than those in above other groups. Conclusion:The level of GP87 will be useful for diagnosis of early gastric cancer and determination of precancerous conditions.