化学发光法检测性激素水平诊断继发性闭经

Diagnosis of the secondary amenorrhea by chemiluminoimmunoassay

目的 探讨临床采用化学发光法诊断继发性闭经的准确性及其意义。方法 采用化学发光法检测 1 2 6例继发性闭经患者血清激素 ,共包括雌二醇 (E2 )、睾酮 (T)、孕酮 (P)、泌乳素 (PRL)、促黄体生成素 (LH)、促卵泡生成素 (FSH) 6项指标。结果 同正常对照组相比 ,闭经妇女的E2 、P明显降低 (P <0 .0 1 ) ,PRL有所上升 (P <0 .0 5 ) ,而T、LH、FSH则无明显改变。其中改变最明显的数据为E2 。结论 化学发光法诊断继发性闭经具有较高的准确性 。

Objective To study the accuracy of chemiluminoimmunoassay to diagnose secondary amenorrhea.Methods The serum hormone levels were measured by chemiluminoimmunoassay in 126 patients with secondary amenorrhea.Six serum hormones are estradiol(E 2),testosterone(T),progesterone(P),prolactin(PRL),luteinization(LH),follicle stimulating hormone(FSH).Results Compared with the contrast group,secondary amenorrhea women had high levels of PRL( P <0.05) and low levels of E 2 and P( P <0.01).Serum levels of T,FSH and LH had no significant change.Conclusion Chemiluminoimmunoassay is a good way for diagnosis of secondary amenorrhea.