摘要
目的 :了解艾滋病患者机会性感染状况 ,分析药物治疗方法。方法 :16例艾滋病患者中 14例出现机会性感染 ,共 2 6例次 ,其中口腔真菌感染 12例 ,肺部感染 4例 ,腹泻 3例 ,隐球菌脑膜炎 1例 ,其他 6例。口腔真菌感染者给予氟康唑 10 0mg ,po ,qd ,疗程 10～ 14d ;肺部感染者给予抗细菌感染 (第三代头孢菌素 )加大剂量磺胺甲唑 甲氧苄啶(SMZ TMP ,3 .0g·d 1 ) ,疗程 10～ 14d ;腹泻患者给予大剂量SMZ TMP(3 .0g·d 1 ) ,疗程 7d ;隐球菌脑膜炎给予两性霉素B(疗程 2周 )加氟康唑 (疗程 2个月 )。结果 :14例机会性感染患者中 ,好转 8例 ,未愈 4例 ,死亡 2例。结论 :艾滋病患者机会性感染较为常见 ,作相应治疗后 ,部分病患者机会性感染得到控制 。
Objective:To study the status and method of drug treatment of opportunistic infections (OI) in patients with AIDS. Methods:OI were found to occur in 14 cases for 26 case times among 16 in patients with AIDS. Patients with thrush (12 case times) were given each 100 mg of fluconazole PO. q.d. for 10-14 consecutive days. Patients with pneumonia (4 case times) were treated with antibacterial drugs (cephalosporin of the third generation) in combination with trimethoprim sulfamethoxazole (SMZ TMP) in high doses (3.0 g·d 1 ·case 1 ) for 10-14 days. Patients with diarrhea (3 case times) were treated with SMZ TMP in high doses (3.0 g·d 1 ·case 1 ) for 7 days. The patient with cryptococcal meningitis (1 case time) was treated with amphotericin B for 2 weeks and fluconazole for 2 months. Results:In the 14 cases of OI treated, 8 showed improvement, 4 proved unaffected and 2 died. Conclusion:Opportunistic infections are frequently encountered in patients with AIDS. In the present study, only a portion of the cases of opportunistic infections responded to treatment with choice drugs.
出处
《医药导报》
CAS
2003年第12期843-844,共2页
Herald of Medicine
关键词
艾滋病
机会性感染
药物治疗
AIDS (Acquired immunodeficiency syndrome)
Opportunistic infections
Drug treatment
