^(99m)Tc-HL91乏氧显像与^(99m)Tc-MIBI亲肿瘤显像诊断肺肿瘤的对比分析

Comparative Study of ^(99m)Tc-HL91 Hypoxia Imaging and ^(99m)Tc-MIBI Tumoraffin in Diagnosis of Lung Neoplasms

目的 :评价 99m Tc- HL 91乏氧显像和 99m Tc- MIBI亲肿瘤显像诊断肺癌的临床价值。方法 :70例肺肿瘤患者行 99m Tc- HL91乏氧显像和 99m Tc- MIBI亲肿瘤显像两项检查 ,对比分析诊断效能和半定量分析结果。结果 :99m Tc- HL91乏氧显像和 99m Tc- MIBI亲肿瘤显像诊断肺癌的灵敏度、特异性和准确率分别为 91.1%、10 0 %、94 .3%和 84 .4 %、76 .0 %、81.4 %。半定量分析结果明显高于 99m Tc- MIBI亲肿瘤显像。两种显像结合诊断肺癌的灵敏度、特异性和准确率分别为95 .6 %、10 0 %、97.1%。结论 :99m Tc- HL91乏氧显像诊断肺癌有较高的临床价值 ,结合 99m Tc- MIBI亲肿瘤显像可进一步提高诊断的准确性。

Objective:To evaluate the clinical value of 99mTc-HL91 hypoxia imaging and 99mTc-MIBI tumoraffin in diagnosis of lung cancer. Methods: 99mTc-HL91 hypoxia imaging and 99mTc-MIBI tumoraffin were performed in 70 patients with Lung Neoplasm. The diagnostic efficacy and the results of half quantitative analysis were compared.Results:The sensitivity, specificity and accuracy of 99mTc-HL91 hypoxia imaging and 99mTc-MIBI tumoraffin was 91.1%100%94.3% and 84.4%76.0%81.4% ,respectively. The results of half quantitative analysis of 99mTc-HL91 hypoxia imaging were higher than those of 99mTc-MIBI tumoraffin. The sensitivity, specificity and accuracy of 99mTc-HL91 hypoxia imaging combined with 99mTc-MIBI tumoraffin in diagnosis of lung cancer was 95.6%100%97.1% respectively.Conclusion: 99mTc-HL91 hypoxia imaging was valuable in diagnosing lung cancer. The diagnostic accuracy was further improved when combined with 99mTc-MIBI tumoraffin.