^(99)Tc^m(V)-DMSA显像诊断急慢性骨关节炎价值的研究

The value studies ^(99)Tc^m(V)-DMSA imaging in the acute and chronic osteoarthritis

目的 :研究99Tcm(V) DMSA(二巯基丁二酸钠 )SPECT显像对急慢性骨关节炎的诊断价值。方法 :急性化脓性骨关节炎患者 17例和慢性骨关节病患者 19例行99Tcm(V) DMSA显像 ,并进行半定量分析。结果 :99Tcm(V) DMSA在急性化脓性骨关节炎病灶处有明显趋骨性浓集 ;而慢性骨关节疾病病灶处99Tcm(V) DMSA显像也有明显的趋骨浓集。半定量分析示99Tcm(V) DMSA显像急性化脓性骨关节炎的放射性靶与非靶组织比值 (L/N)为 3.4 95± 0 .74 2 ,慢性骨关节病的放射性靶与非靶组织比值 (L/N)为 3.14 4± 0 .4 0 0 ,二者之间没有明显差异 (P >0 .0 5 )。结论 :99Tcm(V) DMSA可用于骨组织急慢性炎症的诊断 ,但不能区分骨组织病变的良恶性质。

Objective:To assess the clinical diagnostic values of 99 Tc m(V) DMSA scan in the acute and chronic osteoarthritis.Methods:The seventeen patients referred for investigation of acute osteoarthritis and the nineteen patients referred for investigation of chronic osteoarthritis were studied.In all patients,a bone scan of 99 Tc m(V) DMSA obtained initially,at the same time,to make a semiquantitative analysis.Results:In the acute osteoarthritis group and the chronic osteoarthritis group, 99 Tc m(V) DMSA scan had clearly trend bone accumulation,and there are not clearly different between two groups in 99 Tc m(V) DMSA scan (L/N ratios of acute osteoarthritis group is 3 495±0.742 and L/N ratios of chronic osteoarthritis group is 3.144±0.400,P>0.05)。Conclusion: 99 Tc m(V) DMSA scan may be used to diagnose the bone inflammation.Similitued with 99 Tc m MDP scan, 99 Tc m(V) DMSA scan can not differentiate quality of bone lesion.