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Application Status and Prospect of Bio-artificial Liver

Application Status and Prospect of Bio-artificial Liver
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摘要 Liver failure which can be caused by viral hepatitis,alcohol,drugs,metabolic diseases,autoimmune processes or other fac tors is the end stage of chronic liver disease.Although liver transplantation is currently considered to be the primary treatment measures of chronic liver disease.Due to donor shortages,surgical complications and immune rejection,cell therapy has been extensively studied.?Hepa tocyte transplantation and artificial liver have evolved into a simpler alternative to liver failure treatment.Artificial liver can be used as Liver replacement therapy in patients who were waiting for the liver transplantation with chronic liver disease.The ideal biological artificial liver must have the liver material metabolism,detoxification,synthesis and secretion and other functions.Nowadays bio-artificial liver has carried out a large number of clinical trials and get some progress.?This article is now discuss the status of bio-artificial liver and its re placement therapy prospects. Liver failure which can be caused by viral hepatitis,alcohol,drugs,metabolic diseases,autoimmune processes or other fac tors is the end stage of chronic liver disease.Although liver transplantation is currently considered to be the primary treatment measures of chronic liver disease.Due to donor shortages,surgical complications and immune rejection,cell therapy has been extensively studied.?Hepa tocyte transplantation and artificial liver have evolved into a simpler alternative to liver failure treatment.Artificial liver can be used as Liver replacement therapy in patients who were waiting for the liver transplantation with chronic liver disease.The ideal biological artificial liver must have the liver material metabolism,detoxification,synthesis and secretion and other functions.Nowadays bio-artificial liver has carried out a large number of clinical trials and get some progress.?This article is now discuss the status of bio-artificial liver and its re placement therapy prospects.
出处 《临床医学工程》 2017年第S1期33-36,共4页 Clinical Medicine & Engineering
基金 Guangdong Obers Blood Purification Academician Work station(2013B090400004) Construction of collaborative platform for clinical research and clinical research of blood purifica tion(201604020175) Guangzhou entrepreneurial leader talent/LCY201215 Guangdong University blood purification technology and Engineering Research Center(GCZX-A1104) Guangdong Provincial Center for clinical engineering of blood purification(507204531040) Guangzhou Devel op ment Zone entrepreneur ship leading talent project(2017-L153) Science and technology plan project of Guangdong industrial high and new technology field(2013B010203019)
关键词 Liver failure Biological artificial liver Liver support Liver failure Biological artificial liver Liver support
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