慢性阻塞性肺部疾病血清胃泌素测定的临床意义

CLINICAL SIQNFIFCANCE OF MEASUREMENT OF MEASUREMENT OF SERUM CASTRIN IN THE PATIENTS WITH CHRONIC OBSTRUNT PULMONARY DISCASC(COPD)

本文测定慢性阻塞性肺部疾病(COPD)急性期、缓解期、并发上消化道出血及参照组血清胃泌素浓度.急性期比参照组低(P<0.05).并发上消化道出血组更低(P<0.001),表明胃泌素降低可能 COPD 发生上消化道出血的原因之一.

Serum gastrin was detected in COPD patients by radioimmunoassay.In the pa- tient group its concentration was lower than that in the control group(P<0.05),in patients in acute period it was lower than in releasing period (P<0.05),and in patients associated with up- per digestive tube bleeding (UDTB) its concentration was the lowest.The result shows that se- rum gastrin concentration is correlated with the progress of the disease,and the low gastrin con- centration is perhaps one of the causes of UDTB in COPD patients.